/Duke vs. Louisville odds, line: 2021 ACC Tournament picks, predictions from proven computer model
Duke vs. Louisville odds, line: 2021 ACC Tournament picks, predictions from proven computer model

Duke vs. Louisville odds, line: 2021 ACC Tournament picks, predictions from proven computer model

The Louisville Cardinals and the Duke Blue Devils are set to square off on Wednesday in an ACC Tournament matchup at 6:30 p.m. ET at Greensboro Coliseum. Duke is 12-11 overall, while the Cardinals are 13-6. The Blue Devils are 4-1 against the spread in their last five games as a favorite. The Cardinals, meanwhile, are 6-1 against the spread in their last seven games following an against-the-spread loss.

The Blue Devils are favored by 2.5-points in the latest Louisville vs. Duke odds from William Hill Sportsbook, and the over-under is set at 140. Before entering any Duke vs. Louisville picks, you’ll want to see the college basketball predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of over $2,600 for $100 players on its top-rated college basketball picks against the spread. It has also returned over $400 on all top-rated college basketball picks this season. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Louisville vs. Duke. You can head to SportsLine to see its picks. Here are several college basketball odds for Louisville vs. Duke:

  • Louisville vs. Duke spread: Duke -2.5
  • Louisville vs. Duke over-under: 140 points
  • Louisville vs. Duke money line: Duke -140, Louisville +120

Featured Game | Louisville Cardinals vs. Duke Blue Devils

What you need to know about Louisville

The Cardinals came up short against the Virginia Cavaliers on Saturday, falling 68-58. David Johnson led the way with 14 points. For the season, Johnson is averaging 12.6 points, 5.5 rebounds and 3.3 assists per game.

Louisville went 2-0 against the Blue Devils in the regular season, defeating Duke 70-65 at home on Jan. 23 then besting the Blue Devils 80-73 in overtime on Feb. 27 on the road. Carlik Jones leads Louisville with 17.0 points and 4.6 assists per game, while Samuell Williamson adds 8.1 rebounds per outing. Louisville scores 68.6 points per game and allows 66.3.

What you need to know about Duke

Duke began the ACC Tournament with a victory on Tuesday, downing Boston College 86-51. DJ Steward scored 17 points to lead the Blue Devils. Matthew Hurt leads Duke with 18.2 points and 6.3 rebounds per game, while Jordan Goldwire adds 4.0 assists per outing. Duke scores 76.3 points and allows 72.0 points per game.

Duke is just 1-4 against the spread in its last five games against Louisville. However, the Blue Devils are 4-1 against the spread in their last five games when playing as the favorite.

How to make Louisville vs. Duke picks

The model has simulated Louisville vs. Duke 10,000 times and the results are in. We can tell you that the model is leaning over, and it’s also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Duke vs. Louisville? And which side of the spread cashes in well over 50 percent of simulations? Visit SportsLine now to find out which side of the Louisville vs. Duke spread you need to jump on Wednesday, all from the model that has crushed its college basketball picks, and find out.